Liver fibrosis score in Serum or Plasma Calculated by HepaScore   78894-3

LOINC Code


LOINC code78894-3
nameLiver fibrosis score in Serum or Plasma Calculated by HepaScore
descriptionThis term was created for the HepaScore liver fibrosis test, which is a marker of liver fibrosis in patients with hepatitis C infection. The score ranges from 0 to 1 and is calculated based on four lab tests (GGT, bilirubin, alpha-2-macroglobulin, and hyaluronic acid) plus the patient's age and gender. The HepaScore is reported with a central cut-off of 0.50, with a value ≥ 0.50 indicating that significant liver fibrosis is present (positive predictive value 88%) and a value < 0.50 indicating that advanced fibrosis is absent (negative predictive value 95%) for patients with hepatitis C infection. The HepaScore logistic regression model is as follows: y = exp[-4.185818 - (0.0249 x age) + (0.7464 x sex) + (1.0039 x α2-macroglobulin) + (0.0302 x hyaluronic acid) + (0.0691 x bilirubin) - (0.0012 x GGT)] with age provided in years, male sex = 1, female sex = 0, α2-macroglobulin in g/L, hyaluronate in μg/L, bilirubin in μmol/L, and GGT in U/L. The score itself is calculated as y/(1 +y). [PMID: 16055434]
statusACTIVE

Fully-Specified Name

componentLiver fibrosis score
propertyScore
timePt  =  Point in time:  To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements.
systemSer/Plas
    Ser  =  Serum
    Plas  =  Plasma
scaleQn  =  Quantitative:  The result of the test is a numeric value that relates to a continuous numeric scale. Reported either as an integer, a ratio, a real number, or a range. The test result value may optionally contain a relational operator from the set {<=, <, >, >=}. Valid values for a quantitative test are of the form "7", "-7", "7.4", "-7.4", "7.8912", "0.125", "<10", "<10.15", ">12000", 1-10, 1:256
methodCalculated.HepaScore

Additional Names

short nameLiver fibr score SerPl Calc HepaScore

Basic Attributes

classCHEM
type1  Laboratory
order vs. observationBoth
formula (readable)HepaScore = y/(1+y), where y = exp[-4.185818 - (0.0249 x age) + (0.7464 x sex) + (1.0039 x α2-macroglobulin) + (0.0302 x hyaluronic acid) + (0.0691 x bilirubin) - (0.0012 x GGT)]
example UCUM units{score}
The Unified Code for Units of Measure (UCUM) is a code system intended to include all units of measures being contemporarily used in international science, engineering, and business (www.unitsofmeasure.org)
example unitscore

Associated Observations

LOINC codes that represent optional associated observation(s) for a clinical observation or laboratory test. A LOINC term may represent a single associated observation or panel containing several associated observations.

Member of these Groups

LG19496-5Liver fibrosis score|Score|Pt|ANYBldSerPl

Member of these Panels

78698-8Liver fibrosis score panel - Serum or Plasma Calculated by HepaScore

History/Usage

first released
last updated2.54
last change typeMIN  - change to field other than name

Related Names

Calc
Calc.HepaScore
Calculation
Chemistry
Liver fibr score
Pl
Plasma
Plsm
Point in time
QNT
Quan
Quant
Quantitative
Random
Scale
SerP
SerPl
SerPlas
Serum
Serum or plasma
SR

Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.

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