Gadolinium [Mass/mass] in Tissue   80643-0

LOINC Code


LOINC code80643-0
nameGadolinium [Mass/mass] in Tissue
descriptionDue to its paramagnetic properties, chelated gadolinium is commonly employed as contrast media for magnetic resonance imaging (MRI) and computer tomography (CT) scanning. Gadolinium is eliminated primarily by the renal filtration. In healthy subjects with normal renal function, the plasma half-life of gadolinium is approximately 90 minutes. Patients with reduced renal function exhibit increased gadolinium excretion half-life and may be affected by nephrogenic systemic fibrosis (NSF). In this syndrome, prolonged retention of gadolinium is thought to allow the gadolinium cation to dissociate from its synthetic organic chelator and deposit predominantly in the skin, although other organs may be affected as well. These patients are often severely debilitated by progressive skin thickening and tightening. Fibrosis of skeletal muscle, lungs, liver, testes, and myocardium have also been observed, often with fatal results. Three hemodialysis treatments are required to substantially remove gadolinium from patients with impaired renal function; peritoneal dialysis is not effective.
statusACTIVE

Fully-Specified Name

componentGadolinium
propertyMCnt  =  Mass Content
timePt  =  Point in time:  To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements.
systemTiss  =  Tissue, unspecified
scaleQn  =  Quantitative:  The result of the test is a numeric value that relates to a continuous numeric scale. Reported either as an integer, a ratio, a real number, or a range. The test result value may optionally contain a relational operator from the set {<=, <, >, >=}. Valid values for a quantitative test are of the form "7", "-7", "7.4", "-7.4", "7.8912", "0.125", "<10", "<10.15", ">12000", 1-10, 1:256
method

Additional Names

short nameGadolinium Tiss-mCnt

Basic Attributes

classDRUG/TOX
type1  Laboratory
order vs. observationBoth
example UCUM unitsug/g
The Unified Code for Units of Measure (UCUM) is a code system intended to include all units of measures being contemporarily used in international science, engineering, and business (www.unitsofmeasure.org)
example unitug/g

Associated Observations

LOINC codes that represent optional associated observation(s) for a clinical observation or laboratory test. A LOINC term may represent a single associated observation or panel containing several associated observations.

History/Usage

first released
last updated2.63
last change typeMAJ  - change to name field other than Component;
change reasonUpdated System from "Tissue" to "Tiss" to be consistent with other laboratory tissue terms.

Related Names

DRUG/TOXICOLOGY
Drugs
GADO
Gadolium
Gd
Mass content
Point in time
QNT
Quan
Quant
Quantitative
Random
Tissue
Tissue, unspecified

Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.

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