Sample variant allelic frequency [NFr] 81258-6
LOINC Code
| LOINC code | 81258-6 | ||||||
|---|---|---|---|---|---|---|---|
| name | Sample variant allelic frequency [NFr] | ||||||
| description | The fraction of all reads in a study sample at a given genomic locus that identify the allele (variant) in question. For homozygotes it will be close to 1.0; for heterozygotes it will be close to 0.5. It can be less than 0.5 in the case of mosaics or multiple chromosome, or mixtures of tumor cells and normal cells. This measure is an attribute of the variant and applies when the method is a Next Generation Sequencing (NGS) or similar. Such methods provide many reads from the sample for each locus. To report population allelic frequency, see [LOINC: 92821-8]. Allelic frequency is usually reported as a decimal fraction for both Sample Variant Allelic Frequency and Population Allelic Frequency, although it is occasionally reported as a percent. Special care/caution should be taken when reporting and converting to a decimal fraction. | ||||||
| status | ACTIVE | ||||||
Fully-Specified Name | |||||||
| component | Sample variant allelic frequency | ||||||
| property | NFr = Number Fraction | ||||||
| time | Pt = Point in time: To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements. | ||||||
| system | ^Patient | ||||||
| scale | Qn = Quantitative: The result of the test is a numeric value that relates to a continuous numeric scale. Reported either as an integer, a ratio, a real number, or a range. The test result value may optionally contain a relational operator from the set {<=, <, >, >=}. Valid values for a quantitative test are of the form "7", "-7", "7.4", "-7.4", "7.8912", "0.125", "<10", "<10.15", ">12000", 1-10, 1:256 | ||||||
| method | |||||||
Additional Names | |||||||
| short name | Sample VAF | ||||||
Basic Attributes | |||||||
| class | MOLPATH | ||||||
| type | 1 Laboratory | ||||||
| order vs. observation | Observation | ||||||
| example UCUM units | % The Unified Code for Units of Measure (UCUM) is a code system intended to include all units of measures being contemporarily used in international science, engineering, and business (www.unitsofmeasure.org) | ||||||
| example unit | % | ||||||
Associated Observations | |||||||
LOINC codes that represent optional associated observation(s) for a clinical observation or laboratory test. A LOINC term may represent a single associated observation or panel containing several associated observations. | |||||||
Member of these Panels | |||||||
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History/Usage | |||||||
| test rank | 8648 of 2000 most commonly performed tests by labs in USA | ||||||
| first released | |||||||
| last updated | 2.73 | ||||||
| last change type | MIN - change to field other than name | ||||||
| change reason | Updated Component from "Allelic frequency" to clarify that this term represents the allelic frequency within a study sample, and corrected Term description to describe sample-level allelic frequency rather than population allelic frequency. | ||||||
Related Names | |||||||
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Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.
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