Mi-2 alpha IgG Ab [Presence] in Serum by Line blot   82997-8

LOINC Code


LOINC code82997-8
nameMi-2 alpha IgG Ab [Presence] in Serum by Line blot
descriptionThis term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Various manufacturers classify this method as an immunoblot technique. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method is Line blot.
statusACTIVE

Fully-Specified Name

componentMi-2 alpha Ab.IgG
propertyPrThr  =  Present or threshold:  The Property PrThr stands for “Presence or Threshold”, meaning either a) the actual presence or absence of an analyte, or b) that the amount of analyte detected is over some predetermined threshold.
timePt  =  Point in time:  To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements.
systemSer  =  Serum
scaleOrd  =  Ordinal:  Ordered categorical responses, e.g., 1+, 2+, 3+; positive, negative; reactive, indeterminate, nonreactive.
methodLine blot  =  Line blot:  A membrane strip pre-coated with a specific set of antigens in parallel lines that are incubated with antibodies in order to detect the targets of interest.

Additional Names

short nameMi-2 alpha IgG Ser Ql Line blot

Basic Attributes

classSERO
type1  Laboratory
order vs. observationBoth

Associated Observations

LOINC codes that represent optional associated observation(s) for a clinical observation or laboratory test. A LOINC term may represent a single associated observation or panel containing several associated observations.

History/Usage

first released
last updated2.66
last change typeMIN  - change to field other than name
change reasonThis term was created for an assay that uses a membrane strip pre-coated with a specific set of antigens in parallel lines. Because the antigens are seperated by electrophoresis/chromatographic separation during manufacturing, not during the test procedure itself, this test was assigned a LOINC Method of Immunoassay (IA) and not Immunoblot (IB). However, upon further review of IA, IB, and Immunoblot strip methodologies and regulatory distinctions between these, we changed the Method from IA to Line blot so that users can distinguish between these three Methods. The meaning of the term has not changed since it was created for an IB strip assay as described in the term description.

Related Names

ABS
Aby
Alfa
Antby
Anti
Antibodies
Antibody
Autoantibodies
Autoantibody
CHD2
Chromodomain-helicase-DNA-binding protein 2
Dermatomyositis
Idiopathic Inflammatory Myopathies
II
Immune globulin G
Immunoglobulin G
Inclusion body myositis
MI2
Mi-2 alpha antibody
MSAs
Myositis-specific autoantibodies
Ordinal
Point in time
Polymyositis
PR
QL
Qual
Qualitative
Random
Screen
Serology
Serum
SR

Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.

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