Liver diseases autoimmune IgG panel - Serum or Plasma by Line blot   85092-5

LOINC Code


LOINC code85092-5
nameLiver diseases autoimmune IgG panel - Serum or Plasma by Line blot
descriptionThis panel contains results for the presence of IgG autoantibodies in serum or plasma for the diagnosis of autoimmune liver diseases, including autoimmune hepatitis and primary biliary cirrhosis. This panel was created for, but not limited in use to, the submitter's test strip, a membrane strip pre-coated with the following antigens: AMA-M2, M2-3E, Sp100, PML, gp210, LKM-1, LC-1, SLA/LP, SS-A, Ro-52, Scl-70, CENP A, CENP B and PGDH. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Various manufacturers classify this method as an immunoblot technique. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method is Line blot.
statusACTIVE

Fully-Specified Name

componentLiver diseases autoimmune Ab.IgG panel
property-
timePt  =  Point in time:  To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements.
systemSer/Plas
    Ser  =  Serum
    Plas  =  Plasma
scale-
methodLine blot  =  Line blot:  A membrane strip pre-coated with a specific set of antigens in parallel lines that are incubated with antibodies in order to detect the targets of interest.

Additional Names

short nameLiver diseases IgG Pnl SerPl Line blot

Basic Attributes

classPANEL.SERO
type1  Laboratory
order vs. observationOrder

Panel Components

72318-9Centromere protein A IgG Ab [Presence] in Serum or Plasma by Immunoassay
82913-5Centromere protein B IgG Ab [Presence] in Serum by Line blot
85095-8D-3-phosphoglycerate dehydrogenase IgG Ab [Presence] in Serum by Line blot
82921-8Liver cytosol IgG Ab [Presence] in Serum by Line blot
69952-0Liver kidney microsomal 1 IgG Ab [Presence] in Serum by Immunoassay
82928-3Mitochondria M2 IgG Ab [Presence] in Serum by Line blot
72320-5Mitochondria M2-3E IgG Ab [Presence] in Serum by Immunoassay
82931-7Nuclear pore protein gp210 IgG Ab [Presence] in Serum by Line blot
82923-4PML IgG Ab [Presence] in Serum by Line blot
17570-3SCL-70 extractable nuclear IgG Ab [Presence] in Serum by Immunoassay
82933-3Sjogrens syndrome-A extractable nuclear 52kD IgG Ab [Presence] in Serum by Line blot
17585-1Sjogrens syndrome-A extractable nuclear IgG Ab [Presence] in Serum by Immunoassay
78433-0Soluble liver IgG Ab [Presence] in Serum by Line blot
82932-5sp100 IgG Ab [Presence] in Serum by Line blot

Associated Observations

LOINC codes that represent optional associated observation(s) for a clinical observation or laboratory test. A LOINC term may represent a single associated observation or panel containing several associated observations.

History/Usage

first released
last updated2.68
last change typeNAM  - change to Analyte/Component
change reasonRelease 2.68: COMPONENT: Updated for naming consistency across autoimmune panels.; Previous Releases: This term was created for an assay that uses a membrane strip pre-coated with a specific set of antigens in parallel lines. Because the antigens are seperated by electrophoresis/chromatographic separation during manufacturing, not during the test procedure itself, this test was assigned a LOINC Method of Immunoassay (IA) and not Immunoblot (IB). However, upon further review of IA, IB, and Immunoblot strip methodologies and regulatory distinctions between these, we changed the Method from IA to Line blot so that users can distinguish between these three Methods. The meaning of the term has not changed since it was created for an IB strip assay as described in the term description.

Related Names

Immune globulin G
Immunoglobulin G
Liver diseases IgG Pnl
Pan
PANEL.SEROLOGY
Panl
Pl
Plasma
Plsm
Pnl
Point in time
Random
Serology
SerP
SerPl
SerPlas
Serum
Serum or plasma
SR

Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.

demo
request yours today
subscribe
start today
newsletter
free subscription

Thank you for choosing Find-A-Code, please Sign In to remove ads.