Borrelia afzelii+burgdorferi+garinii IgM band pattern [Interpretation] in Serum by Line blot   87278-8

LOINC Code


LOINC code87278-8
nameBorrelia afzelii+burgdorferi+garinii IgM band pattern [Interpretation] in Serum by Line blot
descriptionThe pattern of reactive bands specific to IgM antibodies associated with Borrelia afzelii, B burgdorferi, and B garinii species in human serum. Antibodies against p39, OspC, Osp17 and VlsE antigens are characterized as highly specific for Borrelia species, whereas p41 shows only limited specificity. The presence of specific bands suggests a recent infection of Lyme disease. This term was created for, but not limited in use to, the Borrelia ViraStripe IgM assay, which uses native, purified antigens immobilized on a test strip to which patient antibodies, if present, will bind. Various manufacturers label this method as an immunoblot technique. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the laboratory assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method is Line blot.
statusACTIVE

Fully-Specified Name

componentBorrelia afzelii+burgdorferi+garinii Ab.IgM band pattern
propertyImp  =  Impression/interpretation of study
timePt  =  Point in time:  To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements.
systemSer  =  Serum
scaleNom  =  Nominal:  Nominal or categorical responses that do not have a natural ordering. (e.g., names of bacteria, reported as answers, categories of appearance that do not have a natural ordering, such as, yellow, clear, bloody.
methodLine blot  =  Line blot:  A membrane strip pre-coated with a specific set of antigens in parallel lines that are incubated with antibodies in order to detect the targets of interest.

Additional Names

short nameB afz+burg+gari IgM Ptrn Ser Line blot

Basic Attributes

classMICRO
type1  Laboratory
order vs. observationObservation

Associated Observations

LOINC codes that represent optional associated observation(s) for a clinical observation or laboratory test. A LOINC term may represent a single associated observation or panel containing several associated observations.

Member of these Panels

87274-7Borrelia afzelii+burgdorferi+garinii IgG and IgM panel - Serum by Line blot

History/Usage

first released
last updated2.67
last change typeMIN  - change to field other than name
change reasonThis term was created for an assay that uses a membrane strip pre-coated with a specific set of antigens in parallel lines. Because the antigens are seperated by electrophoresis/chromatographic separation during manufacturing, not during the test procedure itself, this test was assigned a LOINC Method of Immunoassay (IA) and not Immunoblot (IB). However, upon further review of IA, IB, and Immunoblot strip methodologies and regulatory distinctions between these, we changed the Method from IA to Line blot so that users can distinguish between these three Methods. The meaning of the term has not changed since it was created for an IB strip assay as described in the term description.

Related Names

ABS
Aby
Antby
Anti
Antibodies
Antibody
Autoantibodies
Autoantibody
B afz+burg+gari
B afzelii
Bands
bnd
ID
IgM Patrn
Immune globulin M
Immunoglobulin M
Impression
Impression/interpretation of study
Impressions
Infectious Disease
InfectiousDisease
Interp
Interpretation
Microbiology
Nominal
Patrn
Point in time
Random
Serum
SR

Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.

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