Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ and CD8+ T-cells [Units/volume] corrected for background in Blood 88517-8
LOINC Code
| LOINC code | 88517-8 | ||
|---|---|---|---|
| name | Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ and CD8+ T-cells [Units/volume] corrected for background in Blood | ||
| description | The quantitative levels (corrected for background) for an IFN-gamma response by CD4+ T-helper and CD8+ T cytotoxic lymphocytes stimulated by the presence of TB antigens, specifically ESAT-6 and CFP-10. This term was created for, but not limited in use to, the QuantiFERON-TB Gold Plus test, which includes two tubes with the Mycobacterium tuberculosis (MTB)-complex-associated antigens ESAT-6 and CFP-10 that stimulate a cell-mediated immunity (CMI) response. The first tube contains antigens that stimulate a response from CD4+ T-helper lymphocytes [LOINC: 64084-7], and the second tube (this term) contains the antigens included in tube 1 as well as an additional set of peptides targeting the CMI response from CD8+ cytotoxic T lymphocytes. In the QuantiFERON-TB Gold Plus test, the amount of IFN-gamma is measured by enzyme-linked immunosorbent assay and reported in IU/mL. Results are adjusted for background, heterophile antibody effects, or nonspecific IFN-gamma in blood samples. | ||
| status | ACTIVE | ||
Fully-Specified Name | |||
| component | Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ and CD8+ T-cells^^corrected for background | ||
| property | ACnc = Arbitrary Concentration | ||
| time | Pt = Point in time: To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements. | ||
| system | Bld = Whole blood | ||
| scale | Qn = Quantitative: The result of the test is a numeric value that relates to a continuous numeric scale. Reported either as an integer, a ratio, a real number, or a range. The test result value may optionally contain a relational operator from the set {<=, <, >, >=}. Valid values for a quantitative test are of the form "7", "-7", "7.4", "-7.4", "7.8912", "0.125", "<10", "<10.15", ">12000", 1-10, 1:256 | ||
| method | |||
Additional Names | |||
| short name | M TB IFN-g CD4+CD8+ bckgrnd cor Bld-aCnc | ||
Basic Attributes | |||
| class | MICRO | ||
| type | 1 Laboratory | ||
| order vs. observation | Both | ||
| example UCUM units | [IU]/mL The Unified Code for Units of Measure (UCUM) is a code system intended to include all units of measures being contemporarily used in international science, engineering, and business (www.unitsofmeasure.org) | ||
| example unit | IU/mL | ||
Associated Observations | |||
LOINC codes that represent optional associated observation(s) for a clinical observation or laboratory test. A LOINC term may represent a single associated observation or panel containing several associated observations. | |||
Member of these Panels | |||
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History/Usage | |||
| test rank | 620 of 2000 most commonly performed tests by labs in USA | ||
| first released | |||
| last updated | 2.73 | ||
| last change type | MIN - change to field other than name | ||
| change reason | Changed Component from Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ and CD8+ T-cells^^corrected for background to Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ and CD8+ T-cells^^corrected for background to be consistant with LOINC cell marker naming conventions. | ||
Related Names | |||
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Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.
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