ERBB2 gene duplication in Tumor by FISH 96893-3
LOINC Code
| LOINC code | 96893-3 | ||
|---|---|---|---|
| name | ERBB2 gene duplication in Tumor by FISH | ||
| description | Gene duplication analysis of the ERBB2 gene by FISH studies is performed to guide therapy for patients with primary or metastatic breast tumors. Patients with ERBB2 gene amplification leading to overexpression of the human epidermal growth factor receptor 2 (HER2) protein may be candidates for therapies, such as trastuzumab and pertuzumab, that target HER2. Testing may also be performed to confirm the presence of HER2 amplification in cases with 2+ (low level) or 3+ (high level) HER2 protein overexpression by immunohistochemistry, as well as for certain histologic subtypes with aberrant patterns of HER2 expression seen by immunohistochemistry. The collection of information contained by this term may include the overall result (positive/negative), copy numbers and ratio of HER2 to CEP17, the interpretation, recommendations, and references. For associated observations (result codes) related to this test, see the ERBB2 gene duplication associated observations panel [LOINC: 74885-5]. | ||
| status | ACTIVE | ||
Fully-Specified Name | |||
| component | ERBB2 gene duplication | ||
| property | Find = Finding | ||
| time | Pt = Point in time: To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements. | ||
| system | Tumor | ||
| scale | Doc = Document: A document that could be in many formats (XML, narrative, etc.) | ||
| method | FISH | ||
Additional Names | |||
| short name | ERBB2 gene Dp Tumor FISH | ||
Basic Attributes | |||
| class | MOLPATH | ||
| type | 1 Laboratory | ||
| order vs. observation | Both | ||
Ask At Order Entry | |||
Ask at Order Entry (AOE) observations for a clinical observation or laboratory test. A LOINC term may represent a single AOE observation or a panel containing several AOE observations.
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Associated Observations | |||
LOINC codes that represent optional associated observation(s) for a clinical observation or laboratory test. A LOINC term may represent a single associated observation or panel containing several associated observations. | |||
History/Usage | |||
| first released | |||
| last updated | 2.70 | ||
| last change type | ADD - added | ||
Related Names | |||
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Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.
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