ERBB2 gene duplication in Tumor by FISH   96893-3

LOINC Code


LOINC code96893-3
nameERBB2 gene duplication in Tumor by FISH
descriptionGene duplication analysis of the ERBB2 gene by FISH studies is performed to guide therapy for patients with primary or metastatic breast tumors. Patients with ERBB2 gene amplification leading to overexpression of the human epidermal growth factor receptor 2 (HER2) protein may be candidates for therapies, such as trastuzumab and pertuzumab, that target HER2. Testing may also be performed to confirm the presence of HER2 amplification in cases with 2+ (low level) or 3+ (high level) HER2 protein overexpression by immunohistochemistry, as well as for certain histologic subtypes with aberrant patterns of HER2 expression seen by immunohistochemistry. The collection of information contained by this term may include the overall result (positive/negative), copy numbers and ratio of HER2 to CEP17, the interpretation, recommendations, and references. For associated observations (result codes) related to this test, see the ERBB2 gene duplication associated observations panel [LOINC: 74885-5].
statusACTIVE

Fully-Specified Name

componentERBB2 gene duplication
propertyFind  =  Finding
timePt  =  Point in time:  To identify measures at a point in time. This is a synonym for “spot” or “random” as applied to urine measurements.
systemTumor
scaleDoc  =  Document:  A document that could be in many formats (XML, narrative, etc.)
methodFISH

Additional Names

short nameERBB2 gene Dp Tumor FISH

Basic Attributes

classMOLPATH
type1  Laboratory
order vs. observationBoth

Ask At Order Entry

Ask at Order Entry (AOE) observations for a clinical observation or laboratory test. A LOINC term may represent a single AOE observation or a panel containing several AOE observations.

74885-5ERBB2 gene (HER2) duplication associated observations panel - Tissue by FISH

Associated Observations

LOINC codes that represent optional associated observation(s) for a clinical observation or laboratory test. A LOINC term may represent a single associated observation or panel containing several associated observations.

History/Usage

first released
last updated2.70
last change typeADD  - added

Related Names

Amplification
Cancer
CD340
c-erb B2
Document
Dp
ERBB2 duplication
erb-b2 receptor tyrosine kinase 2
Finding
Findings
Fluorescent in situ hybridization
Genetics
HER2
HER-2
HER-2/neu
Heredity
Heritable
Inherited
MLN 19
Molecular pathology
MOLPATH
NEU
NGL
Oncology
Point in time
Random
TKR1
tumors
tumour
tumours
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene homolog)

Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.

demo
request yours today
subscribe
start today
newsletter
free subscription

Thank you for choosing Find-A-Code, please Sign In to remove ads.